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Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling
With the overload supply of metabolic substrates, excessive fat accumulates in the hepatocytes, accompanied by gradual generation of potential toxic lipid species and the progressive increase in de novo lipogenesis (DNL) in NAFLD (117)
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No pharmacological overlap washout is needed because both drugs are GLP-1 agonists, though re-escalating through the full semaglutide dose ladder is recommended to minimize GI side effects
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Acute cycling exercise induces changes in red blood cell deformability and membrane lipid remodeling
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